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Musellactone, A New Lactone From Musella Lasiocarpa
Author(s) -
Qin Bo,
Shao ZhiYu,
Zeng Wei,
Wang HanQing,
Zhu DaYuan
Publication year - 2006
Publication title -
journal of the chinese chemical society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.329
H-Index - 45
eISSN - 2192-6549
pISSN - 0009-4536
DOI - 10.1002/jccs.200600062
Subject(s) - chemistry , lactone , in vitro , stereochemistry , biochemistry
A new lactone ( 1 ), named musellactone, was isolated from the aerial parts of Musella lasiocarpa , along with eight known compounds. The structures were chemically characterized by spectroscopic methods. Musellactone ( 1 ), and 2‐methyl‐9‐(4′‐hydroxyphenyl)‐phenalen‐1‐one ( 2 ), showed different effects against five bacteria strains, and 1,2,3,4‐tetrahydro‐1,2‐dimethyl‐6,7‐isoquinolinediol ( 3 ), showed significant cytotoxic activities in vitro against KB, HL‐60 and BEL‐7404 human carcinoma cell lines.