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Synthesis and Biological Activity of Some New Pyrazolo[3,4‐b]Pyrazines
Author(s) -
ElEmary Talaat Ibrahim
Publication year - 2006
Publication title -
journal of the chinese chemical society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.329
H-Index - 45
eISSN - 2192-6549
pISSN - 0009-4536
DOI - 10.1002/jccs.200600050
Subject(s) - chemistry , pyrazine , antifungal , antibacterial activity , combinatorial chemistry , stereochemistry , organic chemistry , bacteria , microbiology and biotechnology , genetics , biology
New derivatives of pyrazolo[3,4‐b]pyrazine and related heterocycles were prepared starting from 6‐amino‐3‐methyl‐1‐phenyl‐1 H ‐pyrazolo[3,4‐b]pyrazine‐5‐carbonitrile ( 2 ) and using the key intermediates 4 , 5 , 6 , 14 , 15 and 16 . Some of the prepared compounds were evaluated for their antifungal and antibacterial activities.