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Cytotoxic Acridone Alkaloids from the Stem Bark of Citrus Maxima
Author(s) -
Teng WenYuh,
Huang YuLing,
Shen ChienChang,
Huang RayLing,
Chung RenShih,
Chen ChienChih
Publication year - 2005
Publication title -
journal of the chinese chemical society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.329
H-Index - 45
eISSN - 2192-6549
pISSN - 0009-4536
DOI - 10.1002/jccs.200500180
Subject(s) - acridone , chemistry , alkaloid , cytotoxic t cell , bark (sound) , stereochemistry , botany , biochemistry , in vitro , physics , acoustics , biology
A new acridone alkaloid, 5‐hydroxynoracronycine alcohol (4), along with six known acridone alkaloids, glycocitrine‐I (1), 5‐hydroxynoracronycine (2), citrusinine‐I (3), grandisine‐I (5), natsucitrine‐II (6), and citracridone‐III (7), were isolated from the stem bark of Citrus maxima f. buntan. Their structures were established on the basis of spectroscopic methods. Compounds 1‐4 and 7 were found to be cytotoxic on two tumor cell lines.