Premium
Synthesis and Some Reactions of Coumarin‐3‐yl Crotononitrile Derivatives
Author(s) -
Tamam G. H.,
Bakeer H. M.,
AbdelMotelab R. M.,
Arafa W. A.
Publication year - 2005
Publication title -
journal of the chinese chemical society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.329
H-Index - 45
eISSN - 2192-6549
pISSN - 0009-4536
DOI - 10.1002/jccs.200500171
Subject(s) - chemistry , coumarin , electrophile , reagent , nucleophile , organic chemistry , combinatorial chemistry , medicinal chemistry , catalysis
Several new coumarinyl crotononitriles, 2a‐i, coumarinyl cinnamocoumarines 3a,b, 4‐amino‐3‐(substituted)‐3,4‐dihydrocoumarin 4a‐c and 9a‐c, nicotinic acid derivatives 10a,b and 4‐ethoxy‐3‐substituted‐3,4‐dihydrocoumarins 11, were synthesized from 3‐acetyl and/or 3‐benzoyl coumarin. The behavior of coumarin‐3‐yl crotononitriles 2a,b toward some electrophilic and nucleophilic reagents have been described with the aim of preparing some new heterocyclic compounds.