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Synthesis and Preliminary Anti‐bacterial Activity of Some 4‐Substituted‐ N 1 ‐2‐pyridylsulfanilamide Derivatives
Author(s) -
ElSalam Osama I. Abd,
Mohamed Salwa F.
Publication year - 2005
Publication title -
journal of the chinese chemical society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.329
H-Index - 45
eISSN - 2192-6549
pISSN - 0009-4536
DOI - 10.1002/jccs.200500166
Subject(s) - chemistry , antimicrobial , bacillus subtilis , stereochemistry , organic chemistry , combinatorial chemistry , bacteria , genetics , biology
2‐Amino‐4‐ethoxycarbonylpyridine 1 was used as a starting material in the synthesis of some 4‐substituted‐ N 1 ‐2‐pyridylsulfanilamide derivatives to evaluate their antimicrobial activity. The obtained compounds were of no particular effect against the tested organisms except for a noticeable inhibition of B. subtilis , which was of varying extents but remained clearly significant.