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Regioselective Synthesis of Para‐Bromo Aromatic Compounds
Author(s) -
Khazaei Ardeshir,
Manesh Abbas Amini,
Safi Vahid Reza
Publication year - 2005
Publication title -
journal of the chinese chemical society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.329
H-Index - 45
eISSN - 2192-6549
pISSN - 0009-4536
DOI - 10.1002/jccs.200500082
Subject(s) - chemistry , regioselectivity , benzene , organic chemistry , benzene derivatives , medicinal chemistry , computational chemistry , stereochemistry , chemical synthesis , catalysis , biochemistry , in vitro
Reaction of substituted benzene rings with N‐bromophthalimide, under neutral conditions, gave the corresponding bromo derivatives with a preference for the formation of the para bromo isomer over the ortho isomer. The simple work‐up procedure minimizes loss of product and the yields are good.