z-logo
Premium
Synthesis of Some New Pyrimidothienopyridazines and Related Heterocycles
Author(s) -
Radwan Sh. M.,
ElDean A. M. Kamal,
Bakhite E. A.
Publication year - 2005
Publication title -
journal of the chinese chemical society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.329
H-Index - 45
eISSN - 2192-6549
pISSN - 0009-4536
DOI - 10.1002/jccs.200500046
Subject(s) - chemistry , pyridazine , derivative (finance) , diamine , organic chemistry , medicinal chemistry , combinatorial chemistry , economics , financial economics
5‐Amino‐3,4‐diphenylthieno[2,3‐c]pyridazine‐6‐carbonitrile 2a was reacted with propylene diamine to give tetrahydropyrimidinyl derivative 3 . The latter compound ( 3 ) underwent certain cyclocondensation reactions to produce pyrimidothienopyridazines 4–6 . Also, the reactions of 5‐amino‐3,4‐diphenylthieno[2,3‐c]pyridazine‐6‐carboxamide with heterocyclic aldehydes and/or cycloalkanones were carried out and their products were identified. Moreover, some novel pyridazinothienopyrimidobenzimidazoles 14–17 were synthesized.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here