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First Enantioselective Synthesis of the Neolignans Rhaphidecursinol A and Virolongin B
Author(s) -
Ren Xinfeng,
She Xuegong,
Peng Kun,
Su Ying,
Xie Xingang,
Pan Xinfu,
Zhang Hongbin
Publication year - 2004
Publication title -
journal of the chinese chemical society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.329
H-Index - 45
eISSN - 2192-6549
pISSN - 0009-4536
DOI - 10.1002/jccs.200400144
Subject(s) - enantioselective synthesis , chemistry , sharpless asymmetric dihydroxylation , mitsunobu reaction , stereochemistry , dihydroxylation , absolute configuration , total synthesis , organic chemistry , catalysis
The enantioselective synthesis of the neolignans Rhaphidecursinol A and Virolongin B is reported for the first time. The key reactions in the synthesis were Sharpless asymmetric dihydroxylation and Mitsunobu reaction. The absolute configuration of Rhaphidecursinol A was confirmed.