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Novel Polyhydroxysteroids from the Formosan Soft Coral Sarcophyton Glaucum
Author(s) -
Wang GueyHorng,
Su JuiHsin,
Chen ChienTing,
Duh ChangYih,
Dai ChangFeng,
Sheu JyhHorng
Publication year - 2004
Publication title -
journal of the chinese chemical society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.329
H-Index - 45
eISSN - 2192-6549
pISSN - 0009-4536
DOI - 10.1002/jccs.200400033
Subject(s) - chemistry , coral , cytotoxicity , cancer cell lines , biochemistry , cancer cell , cancer , oceanography , medicine , geology , in vitro
Two novel polyhydroxysteroids, (24 S )‐24‐methylcholestane‐3β,5α,6β,25ξ;,26‐pentol 26‐ n ‐decanoate ( 1 ), (24 S )‐24‐methylcholestane‐3β,5α,6β,25ξ;,26‐pentol 25,26‐diacetate ( 2 ), and three known sterols ( 3‐5 ), have been isolated from a Formosan soft coral Sarcophyton glaucum . The molecular structures of these compounds were determined by spectral methods. The cytotoxicity of these compounds toward various cancer cell lines has also been determined.