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Fused Triazines Via a Tandem Wittig/Ring Closure Strategy: Synthesis of Pyrazolo[5,1‐ c ]‐1,2,4‐Triazines and 1,2,4‐Triazolo[5,1‐ c ]‐1,2,4‐Triazines
Author(s) -
Barsy Magda A.
Publication year - 2003
Publication title -
journal of the chinese chemical society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.329
H-Index - 45
eISSN - 2192-6549
pISSN - 0009-4536
DOI - 10.1002/jccs.200300169
Subject(s) - chemistry , wittig reaction , ring (chemistry) , regioselectivity , triazine , tandem , phenylisocyanate , stereochemistry , closure (psychology) , medicinal chemistry , combinatorial chemistry , organic chemistry , catalysis , materials science , economics , market economy , composite material
A new method for the synthesis of azolo[5,1‐ c ]‐1,2,4‐triazine ring systems is reported by the sequential formation of triazine ring based on the regioselective formation of the azophosphoranes from hydrazonyl chlorides, followed by the intermolecular Wittig reaction with carboxylic acid chlorides, phenylisocyanate, and carbon disulfide.