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Synthesis, Characterization and Bio‐activities of Novel Organotin(IV) Complexes with N ‐Phthaloyl‐D‐valine
Author(s) -
Ashfaq Muhammad,
Baloch Musa Kaleem,
Majeed Abdul,
Khanzada Abdul Wahab Khan,
Shah Wali Ullah
Publication year - 2003
Publication title -
journal of the chinese chemical society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.329
H-Index - 45
eISSN - 2192-6549
pISSN - 0009-4536
DOI - 10.1002/jccs.200300054
Subject(s) - chemistry , trigonal bipyramidal molecular geometry , octahedron , stereochemistry , bipyramid , monomer , antifungal , thiazole , organic chemistry , molecule , crystal structure , medicine , dermatology , polymer
The synthesis and spectroscopic characterization of novel organotin(IV) complexes are described. The monomeric compound possesses trans octahedral, and the dimeric complex is of six‐coordinated skew trapezoidal bipyramidal geometry. The triorganotin(IV) complexes are assigned a polymeric trigonal bipyramidal and a tetrahedral structure. The ED 50 test showed toxicity to brine shrimp naupli and bio‐activities tests of the compounds exhibited antibacterial, antifungal and excellent anti‐tumour activities.