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Synthetic Study of 4‐Substituted Piperidine Ring in Elarofiban, RWJ‐50042, Tirofiban and Paroxetine
Author(s) -
Chang MengYang,
Lin John, YiChung,
Chen ShuiTein,
Chang NeinChen
Publication year - 2002
Publication title -
journal of the chinese chemical society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.329
H-Index - 45
eISSN - 2192-6549
pISSN - 0009-4536
DOI - 10.1002/jccs.200200156
Subject(s) - piperidine , chemistry , ring (chemistry) , paroxetine , stereochemistry , combinatorial chemistry , organic chemistry , serotonin , biochemistry , receptor
A new strategy for synthesizing a 4‐substituted piperidine ring uses the formal [3+3] cycloaddition reaction as the key protocol. This method provides a convenient formal synthesis of elarofiban, RWJ‐50042, tirofiban and paroxetine.
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