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Synthesis of Some New Fused/Spiroheterocyclic Compounds Incorporating Quinone Compounds
Author(s) -
Khalafallah A. K.,
ElAal R. M. Abd,
Kanzi N. A. A. El
Publication year - 2002
Publication title -
journal of the chinese chemical society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.329
H-Index - 45
eISSN - 2192-6549
pISSN - 0009-4536
DOI - 10.1002/jccs.200200061
Subject(s) - chemistry , pyrazolones , thiourea , hydroxylamine , quinoline , chloride , quinone , cycloaddition , urea , organic chemistry , medicinal chemistry , catalysis
A series of fused and spiro pyrazolones, isoxazolines, pyrimidines, β‐lactams, and thiazolidinones incorporating 4‐amino‐2‐methyl‐5,10‐dioxo‐1,5,10,11‐tetrahydrobenz[g]quinoline 3‐carbonitrile 1 and 4‐amino‐2‐methyl‐5,6,11‐trioxo‐1,4,4a,5,6,11,12,12a‐octahydro‐1,12‐diazanaphthacene 3‐carbonitrile 2. 7,8a‐c, 15,16a‐c, 19,20a‐d, 21,22a‐d , have been synthesised by cyclocondensation addition reaction and cycloaddition reaction of hydrazines, hydroxylamine, urea, thiourea, monochloroacetyl chloride and mercaptoacetic acid with the synthesised 15,16a‐c and 17,18a‐c .