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Synthesis of Thiadiazolinylpyrazolopyridine and Pyridopyrazolotriazine Derivatives
Author(s) -
Attaby Fawzy A.,
Elneairy Mohamed A. A.,
Eldin Sanaa M.,
ElLouh Ali K. K.
Publication year - 2001
Publication title -
journal of the chinese chemical society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.329
H-Index - 45
eISSN - 2192-6549
pISSN - 0009-4536
DOI - 10.1002/jccs.200100130
Subject(s) - chemistry , synthon , methylene , reagent , combinatorial chemistry , stereochemistry , mass spectrum , organic chemistry , ion
3‐Diazotized aminopyrazolo[3,4‐b]pyridines 2a,b used as good synthons for the synthesis of 3‐thiadiazolinylpyrazolo[3,4‐b]pyridines 8a,b through their reactions with thiocyanatoacetophenone ( 6 ) and pyrido[2,3:3′,4′]pyrazolo[5,1‐c][1,2,4]triazines 5a‐d via their reactions with several active methylene containing reagents: 3a,b, 12, 16, 20, 23a‐d and 26a‐c . All the structures of the newly synthesized heterocyclic compounds were established by considering the data of IR, 1 H NMR and mass spectra in addition to the synthesis of most newly synthesized heterocyclic compounds via other routes.