Synthesis and Biological Activity of New Selected Different Heterocyclic Nitrogen Compounds Incorporating 1,4‐naphthquinone | Zendy

Khalafallah Ali Kamel | Zendy

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Synthesis and Biological Activity of New Selected Different Heterocyclic Nitrogen Compounds Incorporating 1,4‐naphthquinone

Author(s) -

Khalafallah Ali Kamel

Publication year - 2001

Publication title -

journal of the chinese chemical society

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.329

H-Index - 45

eISSN - 2192-6549

pISSN - 0009-4536

DOI - 10.1002/jccs.200100114

Subject(s) - chemistry , thiourea , pyrazoline , hydroxylamine , urea , condensation , nitrogen , organic chemistry , medicinal chemistry , thermodynamics , physics

Condensation of 1‐phenylnaphthcyclopentan‐2,4,9‐trione ( II ) with aromatic aldehydes yielded the corresponding 3‐benzylidene deivatives ( III a‐f ). Interaction of III a‐f with hydrazines, hydroxylamine, urea and thiourea afforded some new (pyrazoline IV a‐f , V a‐f , Isoxazolino VI a‐f pyrimidinone and/or pyrimidinethione, VII a‐f , VIII a‐f ) derivatives, respectively. Also, a series of some spirocompounds covering β‐lactams and thiazolidinones ( Xg‐j, XIg‐j ) incorporating 1‐phenylnaphthcyclopentan‐2,4,9‐trione were prepared.

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