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Solvent‐Free Synthesis of Heterocyclic Thioureas Using Microwave Technology
Author(s) -
Li JianPing,
Luo QianFu,
Wang YuLu,
Wang Hong
Publication year - 2001
Publication title -
journal of the chinese chemical society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.329
H-Index - 45
eISSN - 2192-6549
pISSN - 0009-4536
DOI - 10.1002/jccs.200100013
Subject(s) - chemistry , microwave , thiourea , microwave oven , solvent , organic chemistry , combinatorial chemistry , physics , quantum mechanics
A new and rapid solvent‐free synthesis of heterocyclic thioureas in a microwave oven has been reported for the first time. Nine heterocyclic thioureas that possess biological activity have been synthesized. The reaction time is short (2–4.5 min) and gives excellent yields (82.9–95.5%).