Premium
Ene Reaction with Pummerer‐type Reaction Intermediate of α‐(Methylthio)‐ N ‐methoxy‐ N ‐methyl Acetamide: A New Synthesis of N ‐methoxy‐ N ‐methyl‐( E,E )‐2,4‐dienamides
Author(s) -
Lin MeiLing,
Wang HueyMin,
Kang IouJiun,
Chen LingChing
Publication year - 2000
Publication title -
journal of the chinese chemical society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.329
H-Index - 45
eISSN - 2192-6549
pISSN - 0009-4536
DOI - 10.1002/jccs.200000150
Subject(s) - chemistry , acetamide , adduct , pummerer rearrangement , ene reaction , medicinal chemistry , organic chemistry , catalysis , acetic anhydride
Pummerer‐type reaction intermediate 2 of α‐(methylthio)‐ N ‐methoxy‐ N ‐methyl acetamide (1) has been found to react with 1‐alkenes to afford ene adducts 3 . N ‐Methoxy‐ N ‐methyl‐( E,E )‐2,4‐dienamides were synthesized from the adducts 3b‐f .
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom