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Studies on Polyfunctionalised Heteroaromatics: Synthesis of Several New Cinnoline and Pyrido[3,4‐c]pyridazine Derivatives
Author(s) -
Barsy Magda A.
Publication year - 2000
Publication title -
journal of the chinese chemical society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.329
H-Index - 45
eISSN - 2192-6549
pISSN - 0009-4536
DOI - 10.1002/jccs.200000131
Subject(s) - cinnoline , pyridazine , chemistry , cyanoacetamide , pyridine , imidazopyridine , combinatorial chemistry , organic chemistry , stereochemistry , medicinal chemistry
One‐pot reaction of ethyl 2‐aryhydrazono‐3‐oxobutyrates with cyanoacetamide afforded pyridazine and pyridine derivatives, which were found to be excellent precursors for the synthesis of different cinnolines and pyrido[3,4‐c]pyridazines, respectively.