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Synthesis of β‐ D ‐Glucopyranosyl(1→3)‐1‐thiol‐β‐glucosamine Disaccharide Derivative as Building Block for the Synthesis of Hyaluronic Acid
Author(s) -
Lin ChunCheng,
Hsu TzuSui,
Lu KuoCheng,
Huang ITing
Publication year - 2000
Publication title -
journal of the chinese chemical society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.329
H-Index - 45
eISSN - 2192-6549
pISSN - 0009-4536
DOI - 10.1002/jccs.200000125
Subject(s) - chemistry , hyaluronic acid , disaccharide , derivative (finance) , thiol , block (permutation group theory) , glucosamine , stereochemistry , organic chemistry , combinatorial chemistry , genetics , geometry , mathematics , financial economics , economics , biology
A practical synthetic method for the title disaccharide 2 is described. Glycosylation using thioglycoside as acceptor and glycosyl imidate as donor was performed with trimethylsilyltriflate as the promoter.