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Synthesis and Antibacterial Activity of s‐Triazoles, s‐Triazolo[3,4‐b]‐1,3,4‐thiadiazines and s‐Triazolo[3,4‐b]‐1,3,4‐thiadiazoles of 5‐Methylisoxazole
Author(s) -
Hui XinPing,
Zhang LinMei,
Zhang ZiYi,
Wang Qin,
Wang Fang
Publication year - 2000
Publication title -
journal of the chinese chemical society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.329
H-Index - 45
eISSN - 2192-6549
pISSN - 0009-4536
DOI - 10.1002/jccs.200000071
Subject(s) - thiadiazoles , chemistry , stereochemistry , combinatorial chemistry , medicinal chemistry
The condensation of 4‐amino‐5‐mercapto‐3‐(5‐methylisoxazol‐3‐yl)‐1,2,4‐triazole with substituted phenacyl bromide, aldehydes, p ‐bromophenylisothiocyanate, aromatic carboxylic acids and oxalic acid, is described. The antibacterial activity of representative compounds was evaluated.