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Phytochemical and Pharmacological Studies on Chinese Paeonia Species
Author(s) -
Ding HsiouYu,
Lin HangChing,
Teng CheMing,
Wu YangChang
Publication year - 2000
Publication title -
journal of the chinese chemical society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.329
H-Index - 45
eISSN - 2192-6549
pISSN - 0009-4536
DOI - 10.1002/jccs.200000051
Subject(s) - chemistry , paeonia suffruticosa , phytochemical , paeonia lactiflora , monoterpene , glycoside , arachidonic acid , kaempferol , traditional medicine , diterpene , thrombin , platelet , biochemistry , stereochemistry , flavonoid , antioxidant , alternative medicine , medicine , pathology , immunology , biology , enzyme
Abstract A new monoterpene glycoside, mudanpioside J ( 3 ), was isolated from the root cortex of Paeonia suffruticosa . Its structure has been established on the basis of spectral evidence. In addition, six known compounds, campesterol ( 4 ), 4‐hydroxyacetopenone ( 5 ), kaempferol ( 6 ), 3‐hydroxy‐4‐methoxybenzoic acid ( 7 ), hederagenin ( 8 ) and galloylpaeoniflorin ( 9 ) were also isolated. A screening test of monoterpene glycosides and aromatic acids derived from P. suffruticosa and P. lactiflora on arachidonic acid, thrombin, collagen and PAF induced rabbit platelet aggregation suggests aromatic acids may play an important role in inhibition of platelet aggregation, inflammation and hemorrhage due to bacterial infection.