Phytochemical and Pharmacological Studies on Chinese  Paeonia  Species | Zendy

Ding HsiouYu | Zendy; Lin HangChing | Zendy; Teng CheMing | Zendy; Wu YangChang | Zendy

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Phytochemical and Pharmacological Studies on Chinese Paeonia Species

Author(s) -

Ding HsiouYu,

Lin HangChing,

Teng CheMing,

Wu YangChang

Publication year - 2000

Publication title -

journal of the chinese chemical society

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.329

H-Index - 45

eISSN - 2192-6549

pISSN - 0009-4536

DOI - 10.1002/jccs.200000051

Subject(s) - chemistry , paeonia suffruticosa , phytochemical , paeonia lactiflora , monoterpene , glycoside , arachidonic acid , kaempferol , traditional medicine , diterpene , thrombin , platelet , biochemistry , stereochemistry , flavonoid , antioxidant , alternative medicine , medicine , pathology , immunology , biology , enzyme

A new monoterpene glycoside, mudanpioside J ( 3 ), was isolated from the root cortex of Paeonia suffruticosa . Its structure has been established on the basis of spectral evidence. In addition, six known compounds, campesterol ( 4 ), 4‐hydroxyacetopenone ( 5 ), kaempferol ( 6 ), 3‐hydroxy‐4‐methoxybenzoic acid ( 7 ), hederagenin ( 8 ) and galloylpaeoniflorin ( 9 ) were also isolated. A screening test of monoterpene glycosides and aromatic acids derived from P. suffruticosa and P. lactiflora on arachidonic acid, thrombin, collagen and PAF induced rabbit platelet aggregation suggests aromatic acids may play an important role in inhibition of platelet aggregation, inflammation and hemorrhage due to bacterial infection.

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