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A Facile Synthesis of Azidoformate via Chloroformate
Author(s) -
Wu PeiLin,
Su ChiaHao,
Gu YiJeng
Publication year - 2000
Publication title -
journal of the chinese chemical society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.329
H-Index - 45
eISSN - 2192-6549
pISSN - 0009-4536
DOI - 10.1002/jccs.200000033
Subject(s) - chemistry , chloroformate , phosgene , acetone , yield (engineering) , tetrahydrofuran , sodium azide , organic chemistry , ethyl chloroformate , sodium hydroxide , activated charcoal , adsorption , materials science , solvent , metallurgy
This work synthesized chloroformates by slowly adding alcohols into a suspension of trichloromethyl chloroformate, instead of phosgene, along with activated charcoal in tetrahydrofuran. This chloroformylation yielded chloroformates in near quantitative yield. The subsequent reaction between chloroformates and sodium azide in dry acetone produced azidoformates in a high yield.