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Rate Study of Samarium Diiodide Reduction of Alkyl Halides and 2‐Heptanone
Author(s) -
Lin TzuenYeuan,
Fun MingRen,
Chang ShihChun
Publication year - 1999
Publication title -
journal of the chinese chemical society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.329
H-Index - 45
eISSN - 2192-6549
pISSN - 0009-4536
DOI - 10.1002/jccs.199900079
Subject(s) - chemistry , halide , alkyl , samarium , ketone , samarium diiodide , medicinal chemistry , grignard reaction , organic chemistry , reagent
Rate constants directly measured from GC‐analyzed method for SmI 2 reduction of alkyl halides were obtained. The rates increase in the orders of primary, secondary, tertiary RX and RCl < RBr < RI as expected. 2‐Heptanone was chosen as the partner of alkyl halide in the samarium Barbier reaction. In the absence of HMPA, the reaction orders of alkyl halide and ketone were determined as first and zero order, respectively.