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Synthesis and Biological Activity of ω‐(5‐Aryl‐1,3,4‐oxadiazol‐2‐thio)‐ and ω‐(5‐Aryl‐1,3,4‐oxadiazol‐2‐thioacetoxyl)‐ω‐(1‐ H ‐1,2,4‐triazol‐1‐yl)acetophenones
Author(s) -
Chu ChangHu,
Sun XiaoWen,
Sun Le,
Zhang ZiYi,
Li ZhiChun,
Liao RenAn
Publication year - 1999
Publication title -
journal of the chinese chemical society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.329
H-Index - 45
eISSN - 2192-6549
pISSN - 0009-4536
DOI - 10.1002/jccs.199900036
Subject(s) - chemistry , thio , aryl , medicinal chemistry , stereochemistry , organic chemistry , alkyl
Eighteen novel ω‐(5‐Aryl‐1,3.4‐oxadiazol‐2‐thio)‐ω‐(1‐ H ‐1,2,4‐triazol‐1‐yl)acetophenones ( 4a‐4i ) and ω‐(5‐Aryl‐1,3,4‐oxadiazol‐2‐thioacetoxyl)‐ω‐(1‐ H ‐1,2,4‐triazol‐1‐yl)acetophenones ( 5a‐5i ) were synthesized. All the compounds synthesized were confirmed by elemental analyses and spectral data. The biological activity of representative compounds was evaluated.