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New Triterpenes from the Heartwood of Melaleuca leucadendron L.
Author(s) -
Lee ChingKuo
Publication year - 1998
Publication title -
journal of the chinese chemical society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.329
H-Index - 45
eISSN - 2192-6549
pISSN - 0009-4536
DOI - 10.1002/jccs.199800048
Subject(s) - chemistry , terpene , squalene , oleanane , organic chemistry , stereochemistry , triterpene , medicine , alternative medicine , pathology
Fourteen chemical constituents were isolated from the CHCl 3 soluble portion of the heartwood of Melaleuca leucadendron L. These compounds include β‐sitosterol (1) , β‐sitostenone (2) , 6‐hydroxy‐4,6‐dimethyl‐3‐hepten‐2‐one (3) , naphthalene (4) , squalene (5) , 2α3β‐dihydroxyurs‐12‐en‐28‐oic acid (6) , 3β‐hydroxylup‐20(29)‐en‐27,28‐dioic acid (7) , 2α,3β‐dihydroxyolean‐12‐en‐28‐oic acid (8) , 3β,23‐dihydroxyolean‐12‐en‐28‐oic acid (9) , 2α,3β,23‐trihydroxyolean‐12‐en‐28‐oic acid (10) , 3β‐ trans‐p ‐coumaroyloxy‐2α,23‐dihydroxyolean‐12‐en‐28‐oic acid (11) , and three novel oleanane derivatives 23‐ trans‐p ‐coumaroyloxy‐2α,3β‐dihydroxyotean‐12‐en‐28‐oic acid (12), 3β‐ trans ‐caffeoyloxy‐2α,23‐dihydroxyolean‐12‐en‐28‐oic acid (13) , and its isomer 3β‐ cis ‐caffeoyloxy‐2α,23‐dihydroxyolean‐12‐en‐28‐oic acid (14) , The three novel compounds were characterized as the two and three O ‐methylated derivatives, respectively.

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