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The Synthesis of 1‐Methyl‐6,7,8,8a‐tetrahydro‐5 H ‐indolizin‐3‐one by the Palladium‐Catalyzed Cyclization of N ‐Bromoacetyl‐2‐vinylpiperidine
Author(s) -
Yang ShyhChyun,
Shea FangRong,
Chung WenHung
Publication year - 1998
Publication title -
journal of the chinese chemical society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.329
H-Index - 45
eISSN - 2192-6549
pISSN - 0009-4536
DOI - 10.1002/jccs.199800046
Subject(s) - chemistry , palladium , catalysis , derivative (finance) , base (topology) , indolizidine , medicinal chemistry , stereochemistry , organic chemistry , mathematical analysis , mathematics , financial economics , economics , alkaloid
N ‐Bromoacetyl‐2‐vinylpiperidine underwent cyclization to give indolizidine derivative in the presence of a base and a catalytic amount of palladium trifluoroacetate.