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Platelet Aggregation Inhibitor from Ganoderma lucidum
Author(s) -
Wu TianShung,
Shi LiShian,
Kuo ShengChu,
Cherng ChingYuh,
Tung ShuFang,
Teng CheMing
Publication year - 1997
Publication title -
journal of the chinese chemical society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.329
H-Index - 45
eISSN - 2192-6549
pISSN - 0009-4536
DOI - 10.1002/jccs.199700026
Subject(s) - chemistry , ganoderma lucidum , platelet aggregation , spectral analysis , stereochemistry , two dimensional nuclear magnetic resonance spectroscopy , platelet , spectroscopy , food science , physics , quantum mechanics , immunology , biology
Lucidenic acid A ( 1 ) and a new lactone, lucidenolactone ( 2 ) were isolated from the fruiting bodies of Ganoderma lucidum . Their structures were elucidated by spectroscopic method and single‐crystal X‐ray analysis. Lucidenolactone ( 2 ) showed significant antiplatelet aggregation activity. The NMR spectral data of lucidenic acid A were also reassigned.