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A Facile Synthesis of Aldehyde and Ketone via Senochemical Barbier Reaction and Oxidation
Author(s) -
Lee Adam ShihYuan,
Kung ChihChun
Publication year - 1997
Publication title -
journal of the chinese chemical society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.329
H-Index - 45
eISSN - 2192-6549
pISSN - 0009-4536
DOI - 10.1002/jccs.199700010
Subject(s) - chemistry , aldehyde , ketone , oxidizing agent , benzene , solvent , iodide , organic chemistry , methyl ketone , methyl iodide , catalysis
Methyl ketone is prepared by a sonochemical Barbier reaction of methyl iodide, magnesium powder and aldehyde in Benzene/THF (9/1) solvent in a commercial ultrasonic cleaning bath (39 kHz), followed by the addition of N‐chlorosuccinimide (NCS) as an oxidizing agent.

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