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Capillary Electrophoresis Separation Techniques and Mechanisms in Dilute Polymer Matrices
Author(s) -
Navin Michael J.,
Morris Michael D.
Publication year - 1995
Publication title -
journal of the chinese chemical society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.329
H-Index - 45
eISSN - 2192-6549
pISSN - 0009-4536
DOI - 10.1002/jccs.199500002
Subject(s) - chemistry , capillary electrophoresis , nucleic acid , chromatography , electrophoresis , resolution (logic) , separation (statistics) , fragment (logic) , electrochromatography , analytical chemistry (journal) , polymer , capillary electrochromatography , capillary action , organic chemistry , machine learning , computer science , composite material , biochemistry , materials science , artificial intelligence , programming language
Capillary electrophoresis in ultradilute derivatized solutions is used to separate nucleic acid fragment mixtures. Pulsed field techniques are used to improve resolution. Protocols in which pulse parameters are varied during the course of the separation are used to increase the range of fragment sizes separated. Fluorescence microscopy is used to study the separation mechanism in ultradilute solution.