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Diels‐Alder Reactions and Synthetic Application of 8‐Trimethylsilyloxy‐1,4‐dioxaspiro[4.5]deca‐6,8‐diene. A Formal Synthesis of (±)‐Compaclin
Author(s) -
Hung ShangCheng,
Liao ChunChen
Publication year - 1994
Publication title -
journal of the chinese chemical society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.329
H-Index - 45
eISSN - 2192-6549
pISSN - 0009-4536
DOI - 10.1002/jccs.199400114
Subject(s) - chemistry , diene , deca , diels–alder reaction , organic chemistry , medicinal chemistry , catalysis , natural rubber
Diels‐Alder reactions of title diene 6 with electron‐deficient dienophiles gave cycloadducts in good yields (83‐96%). The application of cycloadduct 10 to a format synthesis of (±)‐compactin in six steps is described.