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Enantioselective Hydrolysis of 2‐Aryloxypropionyl Derivatives by Penicillin V Amidase
Author(s) -
Chen ShuiTein,
Chang ChunMin,
Lin ShuLing,
Wang KungTsung
Publication year - 1993
Publication title -
journal of the chinese chemical society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.329
H-Index - 45
eISSN - 2192-6549
pISSN - 0009-4536
DOI - 10.1002/jccs.199300078
Subject(s) - chemistry , penicillin , hydrolysis , amidase , enantioselective synthesis , enantiomer , penicillin amidase , catalysis , organic chemistry , chromatography , combinatorial chemistry , antibiotics , biochemistry
Selective hydrolysis of 2‐aryloxypropionyl derivatives 1a‐1e and 2‐phenyloxybutyrate 1f catalyzed by an immobilized penicillin V amidase, Semacylase, was found to show moderately to low enantiomeric excess.
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