Premium
An Alternative Method to Prepare Nitrile Oxides from Primary Nitro Compounds by Using Thionyl Chloride and Triethylamine
Author(s) -
Chen YaoJung,
Li CheNan
Publication year - 1993
Publication title -
journal of the chinese chemical society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.329
H-Index - 45
eISSN - 2192-6549
pISSN - 0009-4536
DOI - 10.1002/jccs.199300030
Subject(s) - nitrile , chemistry , thionyl chloride , triethylamine , nitro , primary (astronomy) , oxide , medicinal chemistry , organic chemistry , chloride , nuclear chemistry , alkyl , physics , astronomy
The dehydration of PhCH 2 NO 2 (1a), PhCOCH 2 NO 2 (1b), and MeOOCCH 2 NO 2 (1c) with SOCl 2 in the presence of Et 3 N gave three corresponding nitrile oxides. Each nitrile oxide was trapped by various dipolarophiles to obtain the cycloadducts of 2‐isoxazolines.