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The Camptothecins: A Reborn Family of Antitumor Agents
Author(s) -
Curran Dennis P.
Publication year - 1993
Publication title -
journal of the chinese chemical society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.329
H-Index - 45
eISSN - 2192-6549
pISSN - 0009-4536
DOI - 10.1002/jccs.199300001
Subject(s) - chemistry , camptothecin , annulation , combinatorial chemistry , stereochemistry , organic chemistry , catalysis
A brief overview of the medicinal chemistry of the camptothecin family of antitumor agents is followed by a summary of a new synthetic approach to this class of compounds. This approach features a new 4 + 1 radical annulation.