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Enantioselective Synthesis of Naproxen
Author(s) -
Duh TsaiHui,
Lin SunJin,
Wang YiFong,
Wu MingJung
Publication year - 1992
Publication title -
journal of the chinese chemical society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.329
H-Index - 45
eISSN - 2192-6549
pISSN - 0009-4536
DOI - 10.1002/jccs.199200080
Subject(s) - chemistry , naproxen , enantioselective synthesis , lipase , yield (engineering) , optically active , catalysis , organic chemistry , resolution (logic) , kinetic resolution , combinatorial chemistry , enzyme , medicine , materials science , alternative medicine , pathology , artificial intelligence , computer science , metallurgy
The optically active naproxen was synthesized in good chemical yield and high optical purity starting from a chiral α‐ketoalcohol which was prepared from enzymatic resolution of the corresponding racemic acetate using lipase as a catalyst.
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