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Additional Isoquinoline Alkaloids from Lltsea Cubeba
Author(s) -
Lee ShoeiSheng,
Chen ChienKuang,
Chen IhSheng,
Liu Karin C. S.
Publication year - 1992
Publication title -
journal of the chinese chemical society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.329
H-Index - 45
eISSN - 2192-6549
pISSN - 0009-4536
DOI - 10.1002/jccs.199200077
Subject(s) - chemistry , isoquinoline , chromatography , stereochemistry
By combination of centrifugal partition chromatography (CPC) and common separation methods, seven additional known bases were isolated and characterized from the reinvestigation of L. cubeba besides three previously isolated bases‐ isocorydine (10), N ‐methyllaurotetanine (9), and boldine (2). They are laurolitsine (1), laurotetanine (3), isoboldine (4), norisocorydine (5), N ‐methyllindcarpine (7), isodomesticine (8), and glaziovine (6). Among these, compound 9 is the most abundant (7.5 × 10 −4 ) and will be modified for pharmacological tests. This work will be of value for chemotaxonomy.