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Stereoselective Synthesis of (+)‐Peperomin C
Author(s) -
Zee ShengHsu,
Chou ShanYen
Publication year - 1991
Publication title -
journal of the chinese chemical society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.329
H-Index - 45
eISSN - 2192-6549
pISSN - 0009-4536
DOI - 10.1002/jccs.199100062
Subject(s) - chemistry , stereoselectivity , ring (chemistry) , alkylation , stereochemistry , carbonyl group , lactone , transformation (genetics) , organic chemistry , catalysis , gene , biochemistry
The stereoselective synthesis of peperomin C is reported. The key steps include the stereoselective alkylation of the substituted diphenylmethyl group to the r‐butyrolactone ring and transformation of the carbonyl group to the other side in the butyrolactone ring by reduction of the lactone carbonyl followed by degradative oxidation.