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Transformation of “Masked” 1,3‐Diols of 1,2‐O‐Isopropylidene‐α‐D‐Erythro‐Hexofuranose into Acyclic Forms. Chirons for Amphotericin B
Author(s) -
Liang David WoeiMing,
FraserReid Bert
Publication year - 1991
Publication title -
journal of the chinese chemical society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.329
H-Index - 45
eISSN - 2192-6549
pISSN - 0009-4536
DOI - 10.1002/jccs.199100032
Subject(s) - chemistry , diastereomer , yield (engineering) , amide , amphotericin b , diol , stereochemistry , transformation (genetics) , organic chemistry , antifungal , biochemistry , microbiology and biotechnology , gene , biology , materials science , metallurgy
3,5‐Dideoxy‐1,2‐ O ‐isopropylidene‐α‐D‐erythro‐hexofuranose 1 was readily converted to dithianyl amide 8, which is a convenient acyclic form of 1,3‐diol, in high yield.