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A Study of the Kinetics of the Sulfation of 2‐Octanol by Sulfamic Acid
Author(s) -
Ho WuHsiung
Publication year - 1987
Publication title -
journal of the chinese chemical society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.329
H-Index - 45
eISSN - 2192-6549
pISSN - 0009-4536
DOI - 10.1002/jccs.198700039
Subject(s) - sulfamic acid , chemistry , sulfation , kinetics , entropy of activation , activation energy , enthalpy , inorganic chemistry , organic chemistry , medicinal chemistry , nuclear chemistry , reaction rate constant , thermodynamics , biochemistry , physics , quantum mechanics
The kinetics of the sulfation of 2‐octanol by sulfamic acid in dimetylformamide were studied. The rate of disappearance of sulfamic acid obeys the rate equation: Rate= k [SA] where [SA] is the concentration of sulfamic acid. The energy and entropy of activation are 3.1 ± 0.6 kcal / mol and 15±2 eu A possible mechanism is as follows: The sulfamic acid reacts with DMF to form DMF·SO 3 which then reacts rapidly with 2‐octanol to form ammonium sec‐octyl sulfate. The kinetics of the sulfation of 2‐octanol by sulfamic acid in dimethyl sulfoxide were also studied. The reaction is described by a similar first‐order equation. The energy and entropy of activation are 33.7±1.0 kcal / mol and 17±3 eu .