Premium
The Synthesis of Alanine Oligopeptides
Author(s) -
Lin D. H.,
Tseng Y. S.,
Chien S. T.,
Wang K. T.
Publication year - 1985
Publication title -
journal of the chinese chemical society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.329
H-Index - 45
eISSN - 2192-6549
pISSN - 0009-4536
DOI - 10.1002/jccs.198500056
Subject(s) - chemistry , oligopeptide , cleave , alanine , reagent , peptide , peptide synthesis , chromatography , solid phase synthesis , amino acid , organic chemistry , biochemistry , enzyme
The oligopeptides of alanine (penta‐, deca‐, and pentadeca‐) were synthesized by solid phase method and new peptide‐resin cleaving reagent TFA‐BBr 3 was used to cleave the peptides from resin‐support. Penta‐alanine was also synthesized by liquid phase for the comparision and FAB‐Mass method was used to determine the molecular weight of penta‐alanine. HPLC separation of these new oligopeptides were described.