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Some Reactions of 5‐(3 or 4‐Pyridyl)‐1,3,4‐Oxadiazoles with Amines and Hydrazines
Author(s) -
Zayed S. A.,
Fakhr I. E.,
Gad F. A.,
Abdulla A.
Publication year - 1984
Publication title -
journal of the chinese chemical society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.329
H-Index - 45
eISSN - 2192-6549
pISSN - 0009-4536
DOI - 10.1002/jccs.198400044
Subject(s) - chemistry , potassium hydroxide , medicinal chemistry , potassium , organic chemistry
2‐Amino‐and 2‐hydrazino‐5‐(3 or 4‐pyridyl)‐1, 3, 4‐oxadiazoles [II i‐k ] have been prepared by racting 2‐chloro derivatives with the corresponding amines or hydrazines, the 2‐hydrazino (II i‐k ) compounds that obtained were heated with carbon disulphide and alcoholic potassium hydroxide where 5‐(3 or 4‐pyridyl)‐1,3,4‐oxadiazolo (2,3‐C)‐1,2,4‐triazole 5‐thione (III a‐c ) were obtained, the given structures were biologically screened.