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Reactions of 3, 5‐Dimethyl‐4‐Carbethoxy‐2‐Cyclohexen‐1‐One at α‐Position
Author(s) -
Rahman A. U.,
Khan M. Y.
Publication year - 1984
Publication title -
journal of the chinese chemical society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.329
H-Index - 45
eISSN - 2192-6549
pISSN - 0009-4536
DOI - 10.1002/jccs.198400023
Subject(s) - chemistry , knoevenagel condensation , alkylation , phenol , acylation , hydrolysis , dimethyl fumarate , organic chemistry , condensation , keto–enol tautomerism , medicinal chemistry , tautomer , catalysis , psychology , physics , psychiatry , multiple sclerosis , thermodynamics
3, 5‐Dimethyl‐4‐carbethoxy‐2‐cyclohexen‐1‐one has been synthesized through the Knoevenagel condensation 1 , which is then subjected to alkylation and acylation at α‐position. The resulting products are hydrolyzed and decarboxylated to α‐substituted cyclohexenones. 3, 5‐Dimethyl‐2‐cyclohexen‐1‐one is converted by N ‐bromosuccinimide to phenol via enolization 2 .