Premium
Synthesis of Cardioactive Steroids III Modified Synthetic Route to Isocardenolide
Author(s) -
Shiao MinJen
Publication year - 1983
Publication title -
journal of the chinese chemical society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.329
H-Index - 45
eISSN - 2192-6549
pISSN - 0009-4536
DOI - 10.1002/jccs.198300043
Subject(s) - chemistry , furan , diene , dissolution , combinatorial chemistry , organic chemistry , natural rubber
A modified synthetic route to isocardenolide (I) via furan intermediate (6) was studied. The diene (4) could easily be synthesized from carbinol (1) or acetate (2). Dissolving metal reduction of diene (4) to Δ 1 , 17β‐furyl compound (6) was successfully achieved.