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The Observation of Metastable Transitions in a High Resolution Double Focussing Mass Spectrometer
Author(s) -
Lin D. P.
Publication year - 1983
Publication title -
journal of the chinese chemical society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.329
H-Index - 45
eISSN - 2192-6549
pISSN - 0009-4536
DOI - 10.1002/jccs.198300033
Subject(s) - chemistry , metastability , mass spectrometry , ion , resolution (logic) , ionization , spectrometer , analytical chemistry (journal) , high resolution , chromatography , optics , organic chemistry , physics , remote sensing , artificial intelligence , computer science , geology
Three metastable transitions are observed with 3 1 5‐ t ‐butyldimethylsiloxy‐dehydrosterone (BDMS‐DHEA) by detecting their daughter ion at m/z 269 in a double focussing mass spectrometer. Because of their specificity, the transitions of molecular ion could be served as quantitation routes for the determination of the steroid in human blood plasma using direct insertion probe with ionization chamber temperature ≥230°C. Thus, as is in MS/MS it would significantly reduce sample work‐up time and possibly eliminate the need for a GC separation in detecting the level of this steroid in human blood.