Synthesis Of N, N′‐Bis(8‐Quinolyl)‐Oligo‐Methylene‐Diamines from 8‐Aminoquinolines | Zendy

Horng Y. S. | Zendy; Hwang C. C. | Zendy; Liao C. C. | Zendy; Liu C. S. | Zendy; Sheu C. F. | Zendy; Yu Y. H. | Zendy

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Synthesis Of N, N′‐Bis(8‐Quinolyl)‐Oligo‐Methylene‐Diamines from 8‐Aminoquinolines

Author(s) -

Horng Y. S.,

Hwang C. C.,

Liao C. C.,

Liu C. S.,

Sheu C. F.,

Yu Y. H.

Publication year - 1980

Publication title -

journal of the chinese chemical society

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.329

H-Index - 45

eISSN - 2192-6549

pISSN - 0009-4536

DOI - 10.1002/jccs.198000011

Subject(s) - chemistry , yield (engineering) , aminoquinolines , alkylation , methylene , medicinal chemistry , combinatorial chemistry , organic chemistry , catalysis , materials science , metallurgy

Various N′,N‐bis(8‐quinolyl) trimethylenediamines 3a‐3e have been prepared from the corresponding 8‐aminoquinolines 1a‐1e by direct N ‐alkylation with 1, 3‐dibromopropane in fair yield (25‐51%). N. N′‐bis(8‐quinolyl) ethylenediamines, 3f and 3g , and N,N′‐bis (8‐(6‐methoxyquinolyl) ]tetramethylenediamine. 3h , may only be synthesized in poor yield via the corresponding oxalamides and succinamide.

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