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Synthesis of 4‐Phenyl and 4′‐Phenyl Chalcones
Author(s) -
Hsu K.K.,
Wu T.S.,
Ski J. Y.
Publication year - 1972
Publication title -
journal of the chinese chemical society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.329
H-Index - 45
eISSN - 2192-6549
pISSN - 0009-4536
DOI - 10.1002/jccs.197200006
Subject(s) - chemistry , potassium hydroxide , sodium hydroxide , condensation , ethanol , catalysis , potassium , organic chemistry , medicinal chemistry , thermodynamics , physics
In order to study the relationship between structure and activity of chalcones, several now 4‐phenyl and 4′‐phenyl chalcones are synthesized by condensation of p ‐phenylbenzaldehyde with, various acetophenones and of p ‐phenylacetophenone with various aldehydes, respectively, in ethanol under the presence of sodium hydroxide or potassium hydroxide as catalyst.