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Studies on the Constituents of Anona Squamosa L.
Author(s) -
Yang TsangHsiung,
Chen ChiMing
Publication year - 1970
Publication title -
journal of the chinese chemical society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.329
H-Index - 45
eISSN - 2192-6549
pISSN - 0009-4536
DOI - 10.1002/jccs.197000031
Subject(s) - chemistry , astringent , traditional medicine , spectral analysis , stereochemistry , botany , food science , medicine , physics , quantum mechanics , spectroscopy , taste , biology
Anona squamosa L. (Fam. Anonaceae) has been used in folk medicine 1 as amebicide, tonic, astringent and has antitumor activity against Ehrlich cancer cell in mice 2,3 . In order to search for the active constituents of Formosan antitumor plants, examination was made on the alkaloids of the roots of Anona squamosa L. Seven alkaloids (A‐G) and an non‐alkaloidal compound (H) were isolated from the basic and n‐hexane fraction respectively. Identification of these bases by spectral analysis and direct comparison of their infrared spectra, tlc and mixed melting point have proved to be non‐phenolic anonaine (I), michelalbine (III), oxoushinsunine (liriodenine) (IV) and phenolic L‐(+)‐reticuline (V), anolobine (VI). Examination of other two minor phenolic Base‐D, mp. 224–226°, Base‐E, mp. 231–233° (decomp) and an non‐alkaloidal crystal‐H, mp. 175–176° are now in progress.