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Cover Image, Volume 35, Issue 32
Publication year - 2014
Publication title -
journal of computational chemistry
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 0.907
H-Index - 188
eISSN - 1096-987X
pISSN - 0192-8651
DOI - 10.1002/jcc.23780
Subject(s) - g protein coupled receptor , cover (algebra) , citation , computer science , function (biology) , information retrieval , image (mathematics) , data science , cognitive science , artificial intelligence , computational biology , receptor , library science , biology , psychology , biochemistry , microbiology and biotechnology , mechanical engineering , engineering
G protein‐coupled receptors (GPCRs) compose one of the largest protein membrane families in our body. These refined receptors have a critical function in many essential regulation pathways and are involved in several severe diseases. Many studies are thus focused on gaining insight into their function. In this review on page 2279 (DOI: 10.1002/jcc.23757 ), Charleen G. Don and Sereina Riniker discuss olfactory receptors, the largest of the GPCR subfamilies. The main focus is on their structural characteristics and the computational techniques that can be used to broaden our current knowledge regarding both GPCRs‐malfunctioning diseases and human odor perception. The image was made using PyMOL.