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Using support vector machines for prediction of protein structural classes based on discrete wavelet transform
Author(s) -
Qiu JianDing,
Luo SanHua,
Huang JianHua,
Liang RuPing
Publication year - 2009
Publication title -
journal of computational chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.907
H-Index - 188
eISSN - 1096-987X
pISSN - 0192-8651
DOI - 10.1002/jcc.21115
Subject(s) - support vector machine , computer science , discrete wavelet transform , sequence (biology) , wavelet , wavelet transform , artificial intelligence , machine learning , pattern recognition (psychology) , algorithm , data mining , chemistry , biochemistry
The prediction of secondary structure is a fundamental and important component in the analytical study of protein structure and functions. How to improve the predictive accuracy of protein structural classification by effectively incorporating the sequence‐order effects is an important and challenging problem. In this study, a new method, in which the support vector machine combines with discrete wavelet transform, is developed to predict the protein structural classes. Its performance is assessed by cross‐validation tests. The predicted results show that the proposed approach can remarkably improve the success rates, and might become a useful tool for predicting the other attributes of proteins as well. © 2008 Wiley Periodicals, Inc. J Comput Chem 2009