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Coronavirus phylogeny based on 2D graphical representation of DNA sequence
Author(s) -
Liao Bo,
Xiang Xuyu,
Zhu Wen
Publication year - 2006
Publication title -
journal of computational chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.907
H-Index - 188
eISSN - 1096-987X
pISSN - 0192-8651
DOI - 10.1002/jcc.20439
Subject(s) - phylogenetic tree , phylogenetics , sequence (biology) , coronavirus , representation (politics) , computational biology , evolutionary biology , genome , dna sequencing , biology , covid-19 , sequence alignment , alignment free sequence analysis , multiple sequence alignment , genetics , dna , gene , peptide sequence , medicine , infectious disease (medical specialty) , disease , pathology , politics , political science , law
A novel coronavirus has been identified as the cause of the outbreak of severe acute respiratory syndrome (SARS). Previous phylogenetic analyses based on sequence alignments show that SARS‐CoVs form a new group distantly related to the other three groups of previously characterized coronaviruses. In this aritcle, a new approach based on the 2D graphical representation of the whole genome sequence is proposed to analyze the phylogenetic relationships of coronaviruses. The evolutionary distances are obtained through measuring the differences among the two‐dimensional curves. © 2006 Wiley Periodicals, Inc. J Comput Chem 27: 1196–1202, 2006