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Graphical approach to analyzing DNA sequences
Author(s) -
Liao Bo,
Ding Kequan
Publication year - 2005
Publication title -
journal of computational chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.907
H-Index - 188
eISSN - 1096-987X
pISSN - 0192-8651
DOI - 10.1002/jcc.20287
Subject(s) - sequence (biology) , computer science , graph , representation (politics) , alignment free sequence analysis , theoretical computer science , computational biology , dna sequencing , dna , algorithm , sequence alignment , genetics , biology , peptide sequence , gene , politics , political science , law
Recently, we proposed a 2D graphical representation of DNA sequence [J Comput Chem 25(2004) 1364–1368]. Based on this representation, we outline one approach to search optimal alignment. We also can judge the mutations between bases and an unknown sequence based on its graph and a known sequence's graph. © 2005 Wiley Periodicals, Inc. J Comput Chem 26: 1519–1523, 2005